Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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181
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195
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181
Tocris Bioscience™ ML 335
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Selective K2P2.1 (TREK-1) and K2P10.1 (TREK-2) activator
| Product Type | Activator |
|---|---|
| Purity | 98% |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C15H14Cl2N2O3S |
| Formula Weight | 373.25 |
182
Tocris Bioscience™ VU 6005649
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Positive allosteric modulators of mGlu7 and mGlu8 receptors. Also NK1 antagonist.
| CAS | 2137047-43-7 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 3-(2,3-Difluoro-4-methoxyphenyl)-2,5-dimethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C16H12F5N3O |
183
Tocris Bioscience™ NNMTi
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Nicotinamide N-methyltransferase (NNMT) inhibitor; promotes myoblast differentiation
| CAS | 42464-96-0 |
|---|---|
| Purity | 97% |
| Chemical Name or Material | 5-Amino-1-methylquinolinium iodide |
| Molecular Formula | C10H11IN2 |
184
Tocris Bioscience™ DPTIP
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent and selective N-SMase2 inhibitor; brain penetrant
| Product Type | Inhibitor |
|---|---|
| Purity | 98% |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C21H18N2O3S |
| Formula Weight | 378.45 |
185
Tocris Bioscience™ VH 032 phenol-alkylC4-amine
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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VH 032 phenol-alkylC4-amine
186
Tocris Bioscience™ BSJ-03-123
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Selective Cdk6 degrader
187
Tocris Bioscience™ Pyridone 6
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent pan-JAK inhibitor; induces intermediate mesoderm; cell-permeable
| Product Type | Inhibitor |
|---|---|
| Purity | 98% |
| Recommended Storage | Store at -20°C |
| Synonym | JAK inhibitor I |
| Molecular Formula | C18H16FN3O |
| Formula Weight | 309.34 |
188
Tocris Bioscience™ YADA
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Green-yellow lucifer yellow-based fluorescent D-amino acid for labeling peptidoglycans in live bacteria
189
Tocris Bioscience™ FM19G11
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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HIF α-subunit inhibitor
| CAS | 329932-55-0 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 2-Oxo-2-(p-tolyl)ethyl 3-(2,4-dinitrobenzamido)benzoate |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C23H17N3O8 |
| Formula Weight | 463.4 |
190
Tocris Bioscience™ Silodosin
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Selective α1A adrenoceptor antagonist (Ki = 0.036 nM)
| CAS | 160970-54-7 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 2,3-Dihydro-1-(3-hydroxypropyl)-5-[(2R)-2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]amino]propyl]-1H-indole-7-carboxamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C25H32F3N3O4 |
| Formula Weight | 495.53 |
191
Tocris Bioscience™ GI 530159
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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TREK1 and TREK2 channel activator
| Product Type | Channel Activator |
|---|---|
| Purity | 99% |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C27H20F6N2O2 |
| Formula Weight | 518.45 |
192
Tocris Bioscience™ BGP 15
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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PARP inhibitor; cytoprotectant
| Product Type | Inhibitor |
|---|---|
| Purity | 98% |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C14H22N4O2.2HCl |
| Formula Weight | 351.27 |
193
Tocris Bioscience™ GSK 2018682
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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S1P1 and S1P5 agonist
| Product Type | Agonist |
|---|---|
| Purity | 98% |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C22H21ClN4O4 |
| Formula Weight | 440.88 |
194
Tocris Bioscience™ FFN 270
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Fluorescent substrate for NET and VMAT2
195
Tocris Bioscience™ CBA
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Selective TRPM4 blocker
| CAS | 351424-20-9 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 4-Chloro-2-[[2-(2-chlorophenoxy)acetyl]amino]benzoic acid |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C15H11Cl2NO4 |
| Formula Weight | 340.16 |