Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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181
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195
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65,077
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181
185
Tocris Bioscience™ 10-Cl-BBQ
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent aryl hydrocarbon receptor (AhR) agonist; orally bioavailable
| CAS | 23982-76-5 |
|---|---|
| Purity | 97% |
| Chemical Name or Material | 10-Chloro-7H-benzimidazo[2,1-a]benz[de]isoquinolin-7-one |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C18H9ClN2O |
| Formula Weight | 304.73 |
186
| CAS | 404950-80-7 |
|---|---|
| Molecular Formula | C21H23N3O2 |
187
| CAS | 20362-31-6 |
|---|---|
| Molecular Formula | C27H34O11 |
188
Tocris Bioscience™ CHDI 113
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent HTT pre-RNA splicing modulator
191
| Target | Additional RTK Inhibitors |
|---|---|
| CAS | 2830555-70-7 |
| Purity | 0.97 |
| Chemical Name or Material | 3-[4-[(Dimethylamino)methyl]phenyl]-N-methyl-N-[5-[3-methyl-5-(1,3,5-trimethyl-1H-pyrazol-4-yl)-2-pyridinyl]-1,3,4-oxadiazol-2-yl]imidazo[1,2-a]pyridine-6-methanamine |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C32H35N9O |
192
Tocris Bioscience™ Pomalidomide 4'-alkylC5-azide
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Cereblon ligand with alkyl linker and terminal azide for onward chemistry
193
Tocris Bioscience™ Avagacestat
Greener Choice
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Highly potent γ-secretase inhibitor; orally bioavailable
| CAS | 1146699-66-2 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | (2R)-2-[[(4-Chlorophenyl)sulfonyl][[2-fluoro-4-(1,2,4-oxadiazol-3-yl)phenyl]methyl]amino]-5,5,5-trifluoropentanamide |
| Recommended Storage | Store at 4°C |
| Synonym | BMS-708163 |
| Molecular Formula | C20H17ClF4N4O4S |
| Formula Weight | 520.89 |
194
Tocris Bioscience™ DR 4485 Hydrochloride
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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High affinity and selective 5-HT7 antagonist; orally bioavailable
| CAS | 402942-53-4 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 6-Chloro-2a-[4-[4-(4-chlorophenyl)-3,6-dihydro-1(2H)-pyridinyl]butyl]-2a,3,4,5-tetrahydrobenz[cd]indol-2(1H)-one hydrochloride |
| Recommended Storage | Desiccate at Room Temperature |
| Molecular Formula | C26H28Cl2N2O.HCl |
| Formula Weight | 491.88 |
195
| CAS | 154598-52-4 |
|---|---|
| Molecular Formula | C14H9ClF3NO2 |